Congenital uterine anomalies in women with recurrentspontaneous abortion: a case control study

AUTHORS : Dutta Malamoni, Mahanta Putul, Das Gokul, Mahanta Jagadish
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Introduction: Recent study reveals that the anatomicalabnormalities of uterus cause recurrent spontaneous abortion(RSA). It also causes miscarriage by interruption of theendometrial vasculature resulting in abnormal and inadequateplacentation. Objective: Aimed to find out the associationof congenital uterine anomalies /Mullerian Duct Anomalies(MDA) with recurrent spontaneous abortion. Materials andmethods: A total of 150 human participants (female) withhistory of 2 or more episodes of recurrent spontaneousabortion were included in this study. A routine investigationsuch as HSG and USG was done to detect congenital uterineanomalies. MRI was done in those cases with suspiciousUSG or HSG findings for confirmation. Similarly 150numbers of fertile females without any history of abortionwere also investigated to detect any congenital uterineanomalies. Results: Out of 150 cases 11 cases reported tohave congenital uterine anomalies. Also, among 150 femaleswithout RSA (Control group), only 3 reported congenitaluterine anomalies. Chi-square test was carried out forindependence of attributes. Conclusion: Patients withcongenital uterine anomalies were commonly found to beassociated with recurrent spontaneous abortion (RSA).Therefore women with recurrent spontaneous abortionshould be investigated by imaging techniques to rule outcongenital uterine anomalies.

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