Congenital uterine anomalies in women with recurrent spontaneous abortion: a case control study

AUTHORS : Dutta Malamoni, Mahanta Putul, Das Gokul, Mahanta Jagadish
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ABSTRACT : Introduction: Recent study reveals that the anatomical abnormalities of uterus cause recurrent spontaneous abortion (RSA). It also causes miscarriage by interruption of the endometrial vasculature resulting in abnormal and inadequate placentation. Objective: Aimed to find out the association of congenital uterine anomalies /Mullerian Duct Anomalies (MDA) with recurrent spontaneous abortion. Materials and methods: A total of 150 human participants (female) with history of 2 or more episodes of recurrent spontaneous abortion were included in this study. A routine investigation such as HSG and USG was done to detect congenital uterine anomalies. MRI was done in those cases with suspicious USG or HSG findings for confirmation. Similarly 150 numbers of fertile females without any history of abortion were also investigated to detect any congenital uterine anomalies. Results: Out of 150 cases 11 cases reported to have congenital uterine anomalies. Also, among 150 females without RSA (Control group), only 3 reported congenital uterine anomalies. Chi-square test was carried out for independence of attributes. Conclusion: Patients with congenital uterine anomalies were commonly found to be associated with recurrent spontaneous abortion (RSA).Therefore women with recurrent spontaneous abortion should be investigated by imaging techniques to rule out congenital uterine anomalies.

Keywords: Miscarriage; mullerian duct anomalies; imaging techniques.

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