Study on in-vitro sensitivity of the bacterial agents responsible for postoperative wound infection

AUTHORS : Sarma MC, Das DK
DOI No. :

ABSTRACT : Introduction : The term post operative wound infection, also known by the term surgical site infection (SSI) is as old as the beginning of surgery. The majority of post operative wound infections (SSI) become apparent within 30 days of an operative procedure and most often between 5th and 10thpost operative days. Extensive use of different antibiotic to cure the post operative sepsis is disadvantageous because it encourages colonization of the body by the organisms resistant to it while it becomes potential source of infection to other. Materials and methods: This was a hospital based observational, descriptive study carried out on 2685 SSI wound samples were included in the present study collected from General Surgery, Orthopaedic, Obstetrics and Gynaecology Departments. Results: 65.8% of the cultured infected wounds were of monomicrobial etiology. Longer durations of surgery was associated with polymicrobial agents, Klebsiella, E. coli and Pseudomonas. Organisms might be transferred to the wound by prolonged contact with the operating staff and equipment, as airborne spread of the Gram negative organisms is rare. Most of the isolates were resistant to the commonly used antibiotics. Conclusion: It has also been suggested that organisms showing multi-resistant character to antibiotics are more virulent than others. Hence rationality in the use of specific antibiotics has become inevitable. Based on the above observations preventive and prophylactic measures a reducing the pre-operative stay to minimum, minimizing the length of operation, treating infection present at other sites on the patient, using a good surgical technique.

Keyword: Surgical site infection (SSI); monomicrobial agents; polymicrobial agents; gram negative; antibiotics.

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