Study on in-vitro sensitivity of the bacterial agentsresponsible for postoperative wound infection

AUTHORS : Sarma MC, Das DK
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Introduction: The term post operative wound infection, alsoknown by the term surgical site infection (SSI) is as old asthe beginning of surgery. The majority of post operativewound infection (SSI) become apparent within 30 days ofan operative procedure and most often between 5th and 10thpost operative days. Extensive use of different antibiotic tocure the post operative sepsis is disadvantageous because itencourages colonization of the body by the organismsresistant to it while it becomes potential source of infectionto other. Materials and methods:This was a hospital basedobservational, descriptive study carried out on 2685 SSIwound samples were included in the present study collectedfrom General Surgery, Orthopedic, Obstetrics andGynaecology Departments. Results:65.8% of the culturedinfected wounds were of monomicrobial etiology. Longerdurations of surgery was associated with polymicrobialagents, Klebsiella, E.coli and Pseudomonas. Organismsmight be transferred to the wound by prolonged contactwith the operating staff and equipment, as airborne spreadof the Gram negative organisms is rare. Most of the isolateswere resistant to the commonly used antibiotics. Conclusion:It has also been suggested that organisms showing multi-resistant character to antibiotics are more virulent thanothers. Hence rationality in the use of specific antibioticshas become inevitable. Based on the above observationspreventive and prophylactic measures a reducing the pre-operative stay to minimum, minimizing the length ofoperation, treating infection present at other sites on thepatient, using a good surgical technique.

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