Bacteriology of chronic respiratory diseases in a tertiary carehospital in Assam

AUTHORS : Das Baishali, Raja Dina
DOI No. : 10.31741/ijhrmlp.v6.i2.2020.7

ABSTRACT :
Introduction: Chronic respiratory diseases constitute a grave problem throughout the world and particularly in middle and low-income countries. The burden of these diseases leads to poor quality of life and disability of affected individuals leading to premature deaths and a great economic loss to their families and society. Materials and Methods: Bronchoalveolar lavage fluid samples of patients with chronic respiratory diseases undergoing bronchoscopy in a tertiary care hospital were collected under aseptic precautions after obtaining approval from the institutional ethical committee. Antibiotic sensitivity testing was performed for the bacterial isolates. Results: 40 out of 110 cases (36.36%) showed the growth of pathogenic bacteria. The most common bacteria isolated were Klebsiella pneumoniae (14.54%) and Pseudomonas aeruginosa (10.90%). The other bacterial isolates were Staphylococcus aureus (2.72%), Enterococcusfaecium (2.72%), Acinetobacter baumannii (1.18%),Enterobacter cloacae (1.18%), Escherichia coli (0.90%) and streptococcus pneumoniae (0.90%). Most of the strains of klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Enterobacter cloacae were sensitive to antibiotics like piperacillin-tazobactam, cefepime, and ciprofloxacin. The gram-positive isolates showed 100%sensitivity to vancomycin and linezolid. Conclusions: Bronchoalveolar lavage has improved sensitivity and specificity in the diagnosis of pulmonary infections.
Keywords: Bronchoalveolar lavage (BAL); antibiotic sensitivity; bacterial isolate; Klebsiella pneumoniae; Staphylococcus aureus


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