Background and aims: Puberty-related health maintenance and promotion is one of the most crucial educational issues and requires adequate knowledge. Adolescence experiences physical, psychological, and social changes during puberty. At the same time, parents' understanding of this issue and related attitudes in early adolescents require information about bodily changes to prevent problems such as guilt and confusion. Thus, the current study investigated mothers' awareness of the health risks associated with puberty in their daughters.  Methods: In this descriptive exploratory research design, 100 parents of adolescents (12-18 years) admitted to different wards and attending OPDs at 151 Base Hospital were selected using a random sampling method and surveyed using a researcher-developed questionnaire. The questionnaire's reliability was calculated using Cronbach's alpha, with tool II at 0.80 and tool III at 0.88. Results: Most parents (64%) had adequate knowledge, and a significant majority (87%) had a positive attitude towards adolescent physical and physiological changes. Knowledge and attitude showed a moderate positive correlation (r = 0.013) with a mean score of 3.33, indicating that better knowledge is associated with a more positive attitude. Conclusion: The findings suggest that parents have a major influence on their adolescents' understanding and experiences during this critical phase. By understanding parents' perspectives, healthcare providers and educators can develop targeted interventions to support parents in guiding their adolescents through these changes, ultimately promoting healthy development and well-being.

Keywords: Parents, attitudes, knowledge, adolescents, physical and physiological changes